Sept 16: ThetaMetrisis joins Hellenic Photonics (HPHOS) cluster

ThetaMetrisis joined Hellenic Photonics (HPHOS) cluster as a standard Enterprise member.

HPHOS is a coalition of innovative Greek companies aiming at to bring together high-tech enterprises and RTOs and creating a dynamic market-oriented and extrovert hub.

For more information on the goals of HPHOS and future plans please visit the cluster’s web-site: www.hphos.gr

Sept 16: Fast simultaneous detection of three pesticides by WLRS

A methodology for the simultaneous determination of pesticides chlorpyrifos, imazalil and thiabendazole in drinking water and wine samples with a biosensor based on White Light Reflectance Spectroscopy was developed. The whole analysis is completed in
G.Koukouvinos, P.S.Petrou, D.Tsounidi, Z.Τsialla, K.Misiakos, D.Goustouridis, A.U.Moreno, A.R Fernandez-Alba, I.Raptis, S.E.Kakabakos Sens. Act. B 238 1214(2017) “Fast and simultaneous detection of three pesticides by a White Light Reflectance Spectroscopy sensing platform”

Miniaturized biosensing system for fast & quantitative prostate specific antigen determination in forensic samples

A fast label-free biosensor based on WLRS for the determination of PSA as semen indicator in forensic samples is developed. The sensor is based on a two-step immunoassay which employs the same polyclonal anti-PSA antibody as capture and detection antibody followed by reaction with streptavidin as a signal enhancement step. Following this protocol, a detection limit of 0.5 ng/mL was achieved and the assay’s linear response range extended up to 500 ng/mL. Thus, taking into account the quantification limit of 1.0 ng/mL and the average PSA concentration in semen (0.2–5.5 mg/mL), semen quantities of a few nanoliters could be detected. A linear correlation was found for semen dilutions ranging from 5000 to 360,000. The lack of interference by other bodily fluids was confirmed by analysing stains of blood, urine and saliva prior to and after the addition of semen. Finally, the sensor was evaluated by analysing 51 forensic casework samples which were also analysed with a semi-quantitative membrane strip test (Seratec® PSA), through microscopic detection of spermatozoa, and male DNA identification through detection of Y chromosome. The results obtained with the sensor were in excellent agreement with those provided by an immunoradiometric assay kit (PSA-RIACT) and in complete agreement with the findings using the membrane strip assay, spermatozoa and Y chromosome detection. The excellent analytical performance and small size of the instrument make the sensor developed an attractive tool for use in forensic evidence screening for semen detection.
G.Koukouvinos, A.Metheniti, Ch.-E.Karachaliou, D.Goustouridis, E.Livaniou, K.Misiakos, I.Raptis, A.Kondili, P.Miniati, P.Petrou, S.Kakabakos Talanta 175 443(2017) “White light reflectance spectroscopy biosensing system for fast quantitative prostate specific antigen determination in forensic samples”

Dec 17: Job opportunity

ThetaMetrisis is currently searching for a motivated Junior Engineer (with degree in Physics, Material Science or related discipline)

for work in the Quality control and Research & Development departments.

More information regarding the available position can be found in the following link:

Junior Engineer

Rapid C-reactive protein determination in whole blood with a WLRS immunosensor for PoC applications

The fast and accurate determination of C-reactive protein (CRP) in human whole blood samples employing a WLRS sensing platform is demonstrated. Each assay cycle was completed in 12 min, including 5-min reaction with the diluted whole blood samples, 3-min with the biotinylated anti-CRP antibody, and 4-min with streptavidin solution. The effect of whole blood on the assay performance was evaluated, and it was found that dilutions as low as 50-times could be employed. Thus, taking into account that the assay had a detection limit of 2.2 ug/L CRP in 50-times diluted sample, whole blood concentrations as low as 110 ug/L could be determined. The excellent analytical characteristics, the short analysis time and the compact instrument size support the applicability of the immunosensor developed for point-of-care CRP determinations.
G.Koukouvinos, D.Goustouridis, K.Misiakos, S.Kakabakos, I.Raptis, P.Petrou Sens. Act. B 260 282(2018) “Rapid C-reactive protein determination in whole blood with a White Light Reflectance Spectroscopy label-free immunosensor for Point-of-Care applications”

We have moved to our new location

We are excited to announce that we are moving to a new location on April 1st. The move was driven by a requirement for more space in all departments, that will enable us to manufacture efficiently a larger quantity of products, and accommodate larger machines to support our growing client base.

Our new address is
Christou Lada 4012132 Athens, Greece

Please use this address for your shipments.

Our telephone numbers (+30-213-0373544, +30-2130373547) remain the same.

FR-uProbe, Film characterization through optical microscope

A new product, FR-uProbe is released. FR-uProbe is a module for reflectance & trasnmittance measurements through any trinocular optical microscope with C-mount.FR-uProbe is the solution for coating characterization applications that require spot size as small as very few micrometers, such as micropatterned surfaces, samples with irregular surfaces that exhibit a high level of scattering light and numerous others.With FR-uProbe, local film thickness, optical constants, reflectance, transmission, and absorbance measurements across UV/Vis/NIR, is just a matter of a click.The standard spot size (area from which the reflectactance or transmittance signal is collected) for 50X objective lens is 5μm and can be as small as 2μm.

 For more information please contact our sales team at: sales@thetametrisis.com